Adult Amblyopia Treatment Study

Amblyopia is characterized by a reduction in visual acuity, contrast sensitivity, and binocular visual functions.  There is very little published on adult amblyopia therapy. This is because clinicians initially believed that amblyopia could not be treated after the end of the critical period.  However, recent studies have suggested that adult amblyopia can be treated. Patching combined with active, near, threshold-training tasks and continuous feedback was employed in these studies.

The purpose of the current study is to use standard amblyopic therapy in addition to an oral supplementation to determine if there is an enhancement in visual performance in the amblyopic eye.

Inclusion criteria/Study specifics:

  • Age > 18 years
  • Best corrected acuities between 20/60 and 20/400 (with E-ETDRS chart)
  • Amblyopia due to anisometropia and/or strabismus
  • A standard amblyopic work up will be performed on all patients to determine if they are eligible for this study
  • Visual acuity and contrast sensitivity function will be measured at each weekly visit
  • Data collection will take approximately six months per subject
  • Prior amblyopia therapy is not an exclusion criteria
  • Subjects will receive amblyopia therapy at no cost

Exclusion criteria:

  • Significant cataract that affects vision
  • Glaucoma
  • Diabetes
  • Uncontrolled high blood pressure
  • Pregnant or expecting to become pregnant during the study period
  • Ocular/systemic diseases that affect contrast sensitivity
  • Renal impairment, liver damage

If you have a potential subject for this study, please contact:

Dr. William Ridder x 714 449 7494                         Dr. Reena Patel x 714 992 7873

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